TMS works by applying magnetic pulses to mood regulating areas of the brain. These pulses are similar to those used during a Magnetic Resonance Imaging (MRI) scan. This magnetic energy changes activity of mood regulating circuits and increases neuroplasticity — that is, the ability of the brain to form new connections among nerve cells. Activating these cells also releases neurotransmitters such as serotonin, norepinephrine, and dopamine, similar to the effects of antidepressant medications. All of these changes can reset the mood regulating mechanisms of the brain, leading to recovery from depression.